Genome‐Scale Mapping of DNase I Hypersensitivity
Abstract DNase I‐seq is a global and high‐resolution method that uses the nonspecific endonuclease DNase I to map chromatin accessibility. These accessible regions, designated a...
Publications
3 shownAn expansive human regulatory lexicon encoded in transcription factor footprints
Regulatory factor binding to genomic DNA protects the underlying sequence from cleavage by DNase I, leaving nucleotide-resolution footprints. Using genomic DNase I footprinting ...
The accessible chromatin landscape of the human genome
DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned the discovery of all classes of cis-regulatory elements including enhancers, promoters, in...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 3,687
- Institution
- University of Washington
External Links
Identifiers
- ORCID
- 0000-0001-6406-8563
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.