James Hicks

Tumour evolution inferred by single-cell sequencing

A plant DNA minipreparation: Version II

Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 gene

Methods in yeast genetics

Transformation of yeast.

A stable leu2- yeast strain has been transformed to LEU2+ by using a chimeric ColE1 plasmid carrying the yeast leu2 gene. We have used recently developed hybridization and restr...

Inferring tumor progression from genomic heterogeneity

Cancer progression in humans is difficult to infer because we do not routinely sample patients at multiple stages of their disease. However, heterogeneous breast tumors provide ...

Genomic Architecture Characterizes Tumor Progression Paths and Fate in Breast Cancer Patients

This study demonstrates the relation among structural genomic alterations, molecular subtype, and clinical behavior and shows that an objective score of genomic complexity can p...