What is “quality of evidence” and why is it important to clinicians?
Guideline developers use a bewildering variety of systems to rate the quality of the evidence underlying their recommendations. Some are facile, some confused, and others sophis...
Publications
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413 publications
Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells
We constructed a series of recombinant genomes which directed expression of the enzyme chloramphenicol acetyltransferase (CAT) in mammalian cells. The prototype recombinant in t...
IDBA-UD: a <i>de novo</i> assembler for single-cell and metagenomic sequencing data with highly uneven depth
Abstract Motivation: Next-generation sequencing allows us to sequence reads from a microbial environment using single-cell sequencing or metagenomic sequencing technologies. How...
Polymer‐Fullerene Bulk‐Heterojunction Solar Cells
Abstract Solution‐processed bulk‐heterojunction solar cells have gained serious attention during the last few years and are becoming established as one of the future photovoltai...
Should We Trust Web-Based Studies? A Comparative Analysis of Six Preconceptions About Internet Questionnaires.
The rapid growth of the Internet provides a wealth of new research opportunities for psychologists. Internet data collection methods, with a focus on self-report questionnaires ...
Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels
New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (...
A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants
Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has been a formidable challenge. Adopting a genome-wide association strategy, we genot...
The FIRST Survey: Faint Images of the Radio Sky at Twenty Centimeters
view Abstract Citations (2408) References (28) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS The FIRST Survey: Faint Images of the Radio Sky a...
Learning Hierarchical Features for Scene Labeling
Scene labeling consists of labeling each pixel in an image with the category of the object it belongs to. We propose a method that uses a multiscale convolutional network traine...
The art of modelling range-shifting species
1. Species are shifting their ranges at an unprecedented rate through human transportation and environmental change. Correlative species distribution models (SDMs) are frequentl...
Safeguarding human health in the Anthropocene epoch: report of The Rockefeller Foundation–Lancet Commission on planetary health
Earth's natural systems represent a growing threat to human health. And yet, global health has mainly improved as these changes have gathered pace. What is the explanation? As a...