Publications

<b>A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53‐null mammary epithelial cell mode</b> .

ABSTRACT Approximately 40% of human breast cancers contain alterations in the tumor suppressor p53. The p53 172R‐H gain‐of‐function mutant (equivalent to the common 175R‐H human...

Mechanism of mitochondrial DNA replication in mouse L-cells: RNA priming during the initiation of heavy-strand synthesis

Animal studies addressing the carcinogenicity of TCDD (or related compounds) with an emphasis on tumour promotion

Dioxin and certain structurally related compounds increase the incidence of liver neoplasms in rodents upon chronic bioassay. Short-term studies indicate the lack of direct DNA-...

Down's syndrome: morphological remodelling and increased complexity in the neuromuscular junction of transgenic CuZn-superoxide dismutase mice

Lipidomic and proteomic analysis of exosomes from mouse cortical collecting duct cells

ABSTRACT Exosomes are endosome‐derived nanovesicles that are involved in cellular communication and signaling. Exosomes are produced by epithelial cells and are found in biologi...

Place-based and IT Mediated ‘Community”

Neighborhoods and whole cities are increasingly being designed with a broadband telecommunications infrastructure that provides access to the Internet and other information and ...

Blockade of Interleukin-6 Signaling Suppresses Not Only Th17 but Also Interphotoreceptor Retinoid Binding Protein–Specific Th1 by Promoting Regulatory T Cells in Experimental Autoimmune Uveoretinitis

PURPOSE. Both Th17 and Th1 cells contribute to experimental autoimmune uveoretinitis (EAU). Interleukin-6 (IL-6) blockade inhibits Th17 differentiation in EAU and potently suppr...

Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice.

Transgenic mice have been used to study gene function and regulation by introducing inducible or tissue-specific transgenes. This approach is generally limited to studying gene ...

High-Redshift Quasars Found in Sloan Digital Sky Survey Commissioning Data. II. The Spring Equatorial Stripe

This is the second paper in a series aimed at finding high-redshift quasars from five-color (u'g'r'i'z') imaging data taken along the Celestial Equator by the Sloan Digital Sky ...

Displacement-loop replication initiation sequence in animal mitochondrial DNA exists as a family of discrete lengths

The single-stranded mitochondrial DNA (mtDNA) displacement-loop initiation sequence (7S mtDNA) is hydrogen-bonded at the origin of replication in animal cell mtDNA. Analysis of ...

Restriction endonuclease cleavage maps of rat and mouse mitochondrial DNAs

Mitochondrial DNA from an Old World mouse, Mus musculus, and from an Old World rat, Rattus norvegicus, contain 19 and 22 distinct sites, respectively, for the 8 restriction endo...

The Infectivity of Polyoma Virus DNA for Mouse Embryo Cells in the Presence of Diethylaminoethyl-dextran

SUMMARY Plaques were produced in mouse-embryo monolayers by infection with polyoma virus DNA in the presence of diethylaminoethyl-dextran. Optimum conditions for plaque assay we...