Abstract

SUMMARY Plaques were produced in mouse-embryo monolayers by infection with polyoma virus DNA in the presence of diethylaminoethyl-dextran. Optimum conditions for plaque assay were established and dose-response relationships for component I and component (II+III) polyoma DNA determined. Efficiencies up to 6 × 105 p.f.u./µg. were obtained for component I DNA.

Keywords

InfectivityEmbryoBiologyPolyoma virusDNADextranVirologyVirusMolecular biologyCell biologyBiochemistry

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Year
1968
Type
article
Volume
3
Issue
3
Pages
371-377
Citations
56
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Donald Warden, H.V. Thorne (1968). The Infectivity of Polyoma Virus DNA for Mouse Embryo Cells in the Presence of Diethylaminoethyl-dextran. Journal of General Virology , 3 (3) , 371-377. https://doi.org/10.1099/0022-1317-3-3-371

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DOI
10.1099/0022-1317-3-3-371