Decision Making in a Fuzzy Environment
By decision-making in a fuzzy environment is meant a decision process in which the goals and/or the constraints, but not necessarily the system under control, are fuzzy in natur...
Publications
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902 publications
A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance
Complex interventions are commonly used in the health and social care services, public health practice, and other areas of social and economic policy that have consequences for ...
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
We identified at least one potential driver mutation in nearly all AML samples and found that a complex interplay of genetic events contributes to AML pathogenesis in individual...
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
UK Research and Innovation, National Institutes for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, Bill & Melinda Gates Foundation, Lemann Foundation, ...
New Perspectives in Cell Adhesion: RGD and Integrins
Rapid progress has been made in the understanding of the molecular interactions that result in cell adhesion. Many adhesive proteins present in extracellular matrices and in the...
Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging
Endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better functional outcomes than s...
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Mutationally corrupted cancer (stem) cells are the driving force of tumor development and progression. Yet, these transformed cells cannot do it alone. Assemblages of ostensibly...
Security in Infancy, Childhood, and Adulthood: A Move to the Level of Representation
We are grateful to the Institute of Human Development, Berkeley, and to the Society for Research in Child Development for funding that made the study of our sample at 6 years po...
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
Age-related clonal hematopoiesis is a common condition that is associated with increases in the risk of hematologic cancer and in all-cause mortality, with the latter possibly d...