The basics of epithelial-mesenchymal transition
The origins of the mesenchymal cells participating in tissue repair and pathological processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly understoo...
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1,267 publications
Chemistry with ADF
Abstract We present the theoretical and technical foundations of the Amsterdam Density Functional (ADF) program with a survey of the characteristics of the code (numerical integ...
TCS: a computer program to estimate gene genealogies
Phylogenies are extremely useful tools, not only for establishing genealogical relationships among a group of organisms or their parts (e.g. genes), but also for a variety of re...
<i>Review</i> : Knowledge Management and Knowledge Management Systems: Conceptual Foundations And Research Issues1,2
Knowledge is a broad and abstract notion that has defined epistemological debate in western philosophy since the classical Greek era. In the past few years, however, there has b...
Cancer Statistics, 2009
Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on...
Free Radicals in the Physiological Control of Cell Function
At high concentrations, free radicals and radical-derived, nonradical reactive species are hazardous for living organisms and damage all major cellular constituents. At moderate...
Measuring the Accuracy of Diagnostic Systems
Diagnostic systems of several kinds are used to distinguish between two classes of events, essentially "signals" and "noise." For them, analysis in terms of the "relative operat...
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
ABSTRACT We have designed a system for targeted gene expression that allows the selective activation of any cloned gene in a wide variety of tissueand cell-specific patterns. Th...
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper ...
The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of developing criteria for the symptomatic predementia phase of Alzheimer's dis...