Dennis W. Dickson

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

JNPL3 transgenic mice expressing a mutant tau protein, which develop neurofibrillary tangles and progressive motor disturbance, were crossed with Tg2576 transgenic mice expressi...

Hippocampal degeneration differentiates diffuse Lewy body disease (DLBD) from Alzheimer's disease

Immunocytochemistry with antibodies to ubiquitin is currently the most sensitive method for detecting cortical Lewy bodies, which are a sine qua non for the diagnosis of diffuse...

Tau and Synuclein and Their Role in Neuropathology

Immunoreactivity profile of hippocampal CA2/3 neurites in diffuse Lewy body disease

The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of developing criteria for the symptomatic predementia phase of Alzheimer's dis...

Neuropathologic Features of Amnestic Mild Cognitive Impairment

The neuropathologic features of aMCI matched the clinical features and seemed to be intermediate between the neurofibrillary changes of aging and the pathologic features of very...

Clinicopathologic and¹¹C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer’s disease spectrum

Thal amyloid phase, which describes the pattern of progressive amyloid-β plaque deposition in Alzheimer's disease, was incorporated into the latest National Institute of Ageing ...

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

We describe a recently recognized disease entity, limbic-predominant age-related TDP-43 encephalopathy (LATE). LATE neuropathological change (LATE-NC) is defined by a stereotypi...