Qualitative research in health care: Analysing qualitative data
This is the second in a series of three articles Contrary to popular perception, qualitative research can produce vast amounts of data. These may include verbatim notes or tra...
Publications
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359 publications
Inference of Population Structure Using Multilocus Genotype Data: Linked Loci and Correlated Allele Frequencies
Abstract We describe extensions to the method of Pritchard et al. for inferring population structure from multilocus genotype data. Most importantly, we develop methods that all...
The MR-Base platform supports systematic causal inference across the human phenome
Results from genome-wide association studies (GWAS) can be used to infer causal relationships between phenotypes, using a strategy known as 2-sample Mendelian randomization (2SM...
Pfam: The protein families database in 2021
Abstract The Pfam database is a widely used resource for classifying protein sequences into families and domains. Since Pfam was last described in this journal, over 350 new fam...
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
Abstract Motivation: Homology models of proteins are of great interest for planning and analysing biological experiments when no experimental three-dimensional structures are av...
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
Funnel plots, and tests for funnel plot asymmetry, have been widely used to examine bias in the results of meta-analyses. Funnel plot asymmetry should not be equated with public...
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in <i>Phenix</i>
Diffraction (X-ray, neutron and electron) and electron cryo-microscopy are powerful methods to determine three-dimensional macromolecular structures, which are required to under...
BEAST 2: A Software Platform for Bayesian Evolutionary Analysis
We present a new open source, extensible and flexible software platform for Bayesian evolutionary analysis called BEAST 2. This software platform is a re-design of the popular B...
A scalable content-addressable network
Hash tables - which map "keys" onto "values" - are an essential building block in modern software systems. We believe a similar functionality would be equally valuable to large ...