Publications

Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units

The SOFA score is a simple, but effective method to describe organ dysfunction/failure in critically ill patients. Regular, repeated scoring enables patient condition and diseas...

Acute Kidney Injury, Mortality, Length of Stay, and Costs in Hospitalized Patients

The marginal effects of acute kidney injury on in-hospital mortality, length of stay (LOS), and costs have not been well described. A consecutive sample of 19,982 adults who wer...

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

Segregation of Form, Color, Movement, and Depth: Anatomy, Physiology, and Perception

Anatomical and physiological observations in monkeys indicate that the primate visual system consists of several separate and independent subdivisions that analyze different asp...

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Fair Allocation of Scarce Medical Resources in the Time of Covid-19

Covid-19 is officially a pandemic. It is a novel infection with serious clinical manifestations, including death, and it has reached at least 124 countries and territories. Alth...

Oncogenic Signaling Pathways in The Cancer Genome Atlas

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

What is “quality of evidence” and why is it important to clinicians?

Guideline developers use a bewildering variety of systems to rate the quality of the evidence underlying their recommendations. Some are facile, some confused, and others sophis...

Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal

Abstract Objective To review and appraise the validity and usefulness of published and preprint reports of prediction models for prognosis of patients with covid-19, and for det...

ChestX-Ray8: Hospital-Scale Chest X-Ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases

The chest X-ray is one of the most commonly accessible radiological examinations for screening and diagnosis of many lung diseases. A tremendous number of X-ray imaging studies ...

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

<h3>Objective.</h3> —To evaluate the efficacy and safety of intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) in patients with acute ischemic strok...