PCAP: A Whole-Genome Assembly Program
We describe a whole-genome assembly program named PCAP for processing tens of millions of reads. The PCAP program has several features to address efficiency and accuracy issues ...
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124 publications
Systemic Overexpression of BCL-2 in the Hematopoietic System Protects Transgenic Mice From the Consequences of Lethal Irradiation
Abstract A new transgenic mouse has been generated in which the proto-oncogene BCL-2 is ubiquitously overexpressed. H2K-BCL-2 transgenic mice overexpress BCL-2 in all cells of t...
<i>Pax-2</i> is required for mesenchyme-to-epithelium conversion during kidney development
ABSTRACT The conversion of mesenchyme to epithelium during the embryonic development of the mammalian kidney requires reciprocal inductive interactions between the ureter and th...
Pivotal roles for eomesodermin during axis formation,epithelium-to-mesenchyme transition and endoderm specification in the mouse
The T-box transcription factor eomesodermin (Eomes) has been implicated as an important component in germ layer induction and patterning in vertebrate embryos. In the mouse, Eom...
c-Src Is Required for Oxidative Stress-mediated Activation of Big Mitogen-activated Protein Kinase 1 (BMK1)
Big mitogen-activated kinase 1 (BMK1) or extracellular signal-regulated kinase-5 (ERK5) has recently been identified as a new member of the mitogen-activated protein kinase fami...
The Discovery of a Luminous [CLC][ITAL]z[/ITAL][/CLC] = 5.80 Quasar from the Sloan Digital Sky Survey
We present observations of SDSSp J104433.04--012502.2, a luminous quasar at z=5.80 discovered from Sloan Digital Sky Survey (SDSS) multicolor imaging data. This object was selec...
Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice
Alzheimer's disease presents morphologically with senile plaques, primarily made of extracellular amyloid-beta (A beta) deposits, and neurofibrillary lesions, which consist of i...
Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.
A combination of histological stains has been used to obtain maximum contrast between capillary endothelial cells, fibroblasts, and parenchymal cells in sections of a transplant...
Candidate RR Lyrae Stars Found in Sloan Digital Sky SurveyCommissioning Data*
We present a sample of 148 candidate RR Lyrae stars selected from Sloan Digital Sky Survey (SDSS) commissioning data for about 100 deg 2 of sky surveyed twice with Δ t = 1.9946 ...