Jos Domen - Researcher Profile | RDL Research Database

Publications

2 shown

Systemic Overexpression of BCL-2 in the Hematopoietic System Protects Transgenic Mice From the Consequences of Lethal Irradiation

Jos Domen , Kimberly L. Gandy , Irving L. Weissman

Abstract A new transgenic mouse has been generated in which the proto-oncogene BCL-2 is ubiquitously overexpressed. H2K-BCL-2 transgenic mice overexpress BCL-2 in all cells of t...

1998 Blood 291 citations

Hematopoietic Stem Cells Need Two Signals to Prevent Apoptosis; Bcl-2 Can Provide One of These, Kitl/C-KIT Signaling the Other

Jos Domen , Irving L. Weissman

Growth factors can cause cells to proliferate, differentiate, survive, or die. Distinguishing between these responses is difficult in multicellular, multiparameter systems. Yet ...

2000 The Journal of Experimental Medicine 217 citations

Frequent Co-Authors

Kimberly L. Gandy

Stanford University

Irving L. Weissman

Stanford University

Researcher Info

h-index: 2
Publications: 2
Citations: 508
Institution: Stanford University

External Links

Google Scholar

Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.