Early Lactate-Guided Therapy in Intensive Care Unit Patients
In patients with hyperlactatemia on ICU admission, lactate-guided therapy significantly reduced hospital mortality when adjusting for predefined risk factors. As this was consis...
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81 publications
The Influence of Hospital Volume on Survival after Resection for Lung Cancer
Patients who undergo resection for lung cancer at hospitals that perform large numbers of such procedures are likely to survive longer than patients who have such surgery at hos...
Prediction of Mortality and Morbidity With a 6-Minute Walk Test in Patients With Left Ventricular Dysfunction
<h3>Objective.</h3> —To study the potential usefulness of the 6-minute walk test, a self-paced submaximal exercise test, as a prognostic indicator in patients with left ventricu...
Simplified Therapeutic Intervention Scoring System
Objectives To validate a simplified version of the Therapeutic Intervention Scoring System, the TISS-28, and to determine the association of TISS-28 with the time spent on score...
Maternal Attachment
Abstract To determine whether present hospital practices may affect later maternal behavior, we placed 28 primiparous women in two study groups shortly after delivery of normal ...
Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy.
Of the 180 children admitted to hospitals in Tyneside in the first year of life with proved respiratory syncytial virus lower respiratory tract infection, 130 were seen for revi...
Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality*
Implementation of a severe sepsis bundle using a quality improvement feedback to modify physician behavior in the emergency department setting was feasible and was associated wi...
Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China
Abstract Background In December 2019, a series of pneumonia cases of unknown cause emerged in Wuhan, Hubei, China. In this study, we investigate the clinical and laboratory feat...
Gender-Related Differences in Acute Aortic Dissection
Background— Few data exist on gender-related differences in clinical presentation, diagnostic findings, management, and outcomes in acute aortic dissection (AAD). Methods and Re...
Snoring as a risk factor for ischaemic heart disease and stroke in men.
The association of snoring with ischaemic heart disease and stroke was studied prospectively in 4388 men aged 40-69. The men were asked, in a questionnaire sent to them, whether...
Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis
Background: There is controversy about the outcome of patients with acute myocarditis (AM), and data are lacking on how patients admitted with suspected AM are managed. We repor...