Publications

Integrated analysis of multimodal single-cell data

ezSingleCell is an interactive and easy-to-use application for the analysis of multiple single-cell and spatial omics data types for biologists. It combines the best-performing ...

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons

This study evaluated a modified, timed version of the “Get‐Up and Go” Test (Mathias et al, 1986) in 60 patients referred to a Geriatric Day Hospital (mean age 79.5 years). The p...

The blockade of immune checkpoints in cancer immunotherapy

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

Abstract: We present the derivation of a new molecular mechanical force field for simulating the structures, conformational energies, and interaction energies of proteins, nucle...

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

Anti-PD-1 antibody produced objective responses in approximately one in four to one in five patients with non-small-cell lung cancer, melanoma, or renal-cell cancer; the adverse...

An obesity-associated gut microbiome with increased capacity for energy harvest

WordNet: An Electronic Lexical Database

Part 1 The lexical database: nouns in WordNet, George A. Miller modifiers in WordNet, Katherine J. Miller a semantic network of English verbs, Christiane Fellbaum design and imp...

Pathogen Recognition and Innate Immunity

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

The HER-2/ neu oncogene is a member of the erb B-like oncogene family, and is related to, but distinct from, the epidermal growth factor receptor. This gene has been shown to be...

Planetary boundaries: Guiding human development on a changing planet

Crossing the boundaries in global sustainability The planetary boundary (PB) concept, introduced in 2009, aimed to define the environmental limits within which humanity can safe...