Publications

Transcriptome and genome sequencing uncovers functional variation in humans

Gene-Expression Profiles in Hereditary Breast Cancer

Significantly different groups of genes are expressed by breast cancers with BRCA1 mutations and breast cancers with BRCA2 mutations. Our results suggest that a heritable mutati...

De novo mutations in schizophrenia implicate synaptic networks

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Hill shading and the reflectance map

Abstract-Shaded overlays for maps give the user an immediate appreciation for the surface topography since they appeal to an important visual depth cue. A brief review of the hi...

The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression

As defined by the DSM-IV, BPD is highly heritable. There are substantial genetic and nonshared environmental correlations between mania and depression, but most of the genetic v...

A roadmap for rapid decarbonization

Emissions inevitably approach zero with a “carbon law”

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

Heritable variation in complex traits is generally considered to be conferred by common DNA sequence polymorphisms. We tested whether rare DNA sequence variants collectively con...

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

Museums in Motion: An Introduction to the History and Functions of Museums

Anyone interested in The University of Iowa will enjoy browsing through this storehouse of bibliographic information.Earl Rogers of the University Archives has compiled some 575...

Decisive Data Sets in Phylogenomics: Lessons from Studies on the Phylogenetic Relationships of Primarily Wingless Insects

Phylogenetic relationships of the primarily wingless insects are still considered unresolved. Even the most comprehensive phylogenomic studies that addressed this question did n...

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Recent observations of (6)Li in metal poor stars suggest a large production of this isotope during big bang nucleosynthesis (BBN). In standard BBN calculations, the (2)H(α,γ)(6)...