The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression

Abstract

As defined by the DSM-IV, BPD is highly heritable. There are substantial genetic and nonshared environmental correlations between mania and depression, but most of the genetic variance in liability to mania is specific to the manic syndrome.

Keywords

ManiaBipolar disorderConcordanceProbandHeritabilityTwin studyGenetic correlationPsychologyDepression (economics)Research Diagnostic CriteriaGenetic modelPsychiatryConfidence intervalDizygotic twinClinical psychologyInternal medicineMedicineGeneticsSchizophrenia (object-oriented programming)Genetic variationMoodBiologyPopulation

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Publication Info

Year: 2003
Type: article
Volume: 60
Issue: 5
Pages: 497-497
Citations: 1220
Access: Closed

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APA Style

                            
                                
                                    Peter McGuffin, 
                                
                                    Frühling Rijsdijk, 
                                
                                    Martin Andrew
                                
                                et al.
                            
                            (2003). 
                            The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression. 
                            Archives of General Psychiatry
                            , 60
                            (5)
                            , 497-497.
                            https://doi.org/10.1001/archpsyc.60.5.497
                        

Identifiers

DOI: 10.1001/archpsyc.60.5.497