An emerging consensus on grading recommendations?
Clinical practice guidelines have improved in quality over the past 10 years by adhering to a few basic principles, such as conducting thorough systematic reviews of relevant ev...
Publications
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247 publications
Empirical graph Laplacian approximation of Laplace–Beltrami operators: Large sample results
Let ${M}$ be a compact Riemannian submanifold of ${{\\bf R}^m}$ of dimension\n$\\scriptstyle{d}$ and let ${X_1,...,X_n}$ be a sample of i.i.d. points in ${M}$\nwith uniform dist...
Archiving next generation sequencing data
Next generation sequencing platforms are producing biological sequencing data in unprecedented amounts. The partners of the International Nucleotide Sequencing Database Collabor...
Determinants of exercise during colorectal cancer treatment: an application of the theory of planned behavior.
Oncology nurses need to have an understanding of motivational factors related to exercise during cancer treatment to be able to assist patients with cancer to initiate and maint...
A systematic review of the clinical effectiveness of first-line chemotherapy for adult patients with locally advanced or metastatic non-small cell lung cancer
Our aim was to evaluate the clinical effectiveness of chemotherapy treatments currently licensed in Europe and recommended by the National Institute for Health and Care Excellen...
A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of <i>EGFR</i>
Abstract Background Malignant astrocytic gliomas in children show a remarkable biological and clinical diversity. Small in-frame insertions or missense mutations in the epiderma...
Secular Trends in Mortality From Common Cancers in the United States by Educational Attainment, 1993–2001
The recent declines in death rates from major cancers in the United States mainly reflect declines in more highly educated individuals.
Ubiquitous presence of cat allergen in cat-free buildings: probable dispersal from human clothing.
Fel d I has been found in almost all houses investigated, including those in which cats have never been present. These observations have not been explained. We measured Fel dI i...
Prognostic value of intratumoral CD8<sup>+</sup> T lymphocyte in extrahepatic bile duct carcinoma as essential immune response
Abstract Background and Objectives Tumor‐infiltrating lymphocytes form an important aspect of the host defense against an expanding neoplasm. CD8 + T cells have been identified ...
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
In the 2008 WHO classification, chronic myeloid malignancies that share both myelodysplastic and myeloproliferative features define the myelodysplastic/myeloproliferative group,...
The prognostic value of peritumoral regulatory T cells and its correlation with intratumoral cyclooxygenase‐2 expression in clear cell renal cell carcinoma
OBJECTIVE To investigate the prognostic value of regulatory T cells (Tregs) and its correlation with cyclooxygenase‐2 (COX‐2) expression in clear cell renal cell carcinoma (RCC)...