Cancer immunotherapy using checkpoint blockade
The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses i...
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1,246 publications
World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)
An unprecedented outbreak of pneumonia of unknown aetiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus was identified as the causative ...
On the psychology of prediction.
In this paper, we explore the rules that determine intuitive predictions and judgments of confidence and contrast these rules to the normative principles of statistical predicti...
Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
Pembrolizumab had an acceptable side-effect profile and showed antitumor activity in patients with advanced non-small-cell lung cancer. PD-L1 expression in at least 50% of tumor...
Scaling Theory of Localization: Absence of Quantum Diffusion in Two Dimensions
Arguments are presented that the $T=0$ conductance $G$ of a disordered electronic system depends on its length scale $L$ in a universal manner. Asymptotic forms are obtained for...
Oxidants, antioxidants, and the degenerative diseases of aging.
Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage...
Review of Particle Physics
Abstract The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 2,143 new measurements from 709 papers, we list, evaluate, and ave...