An improved Bonferroni procedure for multiple tests of significance
Journal Article An improved Bonferroni procedure for multiple tests of significance Get access R. J. SIMES R. J. SIMES Ludwig Institute for Cancer Research, University of Sydney...
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Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes
Skeletal muscle is strongly dependent on oxidative phosphorylation for energy production. Because the insulin resistance of skeletal muscle in type 2 diabetes and obesity entail...
Coronavirus Infections—More Than Just the Common Cold
In this Viewpoint Anthony Fauci and colleagues review the emergence of pathogenic human coronaviruses (SARS-Cov and MERS-CoV) as background for discussing a rapidly spreading no...
Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention
Treatment with beta carotene, vitamin A, and vitamin E may increase mortality. The potential roles of vitamin C and selenium on mortality need further study.
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that selectively affects optic nerves and spinal cord. It is considered a severe variant of multiple sclerosi...
Epithelial-mesenchymal transition and its implications for fibrosis
Epithelial to mesenchymal transition (EMT) is a central mechanism for diversifying the cells found in complex tissues. This dynamic process helps organize the formation of the b...
The 2dF Galaxy Redshift Survey: spectra and redshifts
The 2dF Galaxy Redshift Survey (2dFGRS) is designed to measure redshifts for approximately 250 000 galaxies. This paper describes the survey design, the spectroscopic observatio...
Evidence-Based Health Policy—Lessons from the Global Burden of Disease Study
The Global Burden of Disease Study, a comprehensive regional and global assessment of mortality and disability from 107 diseases and injuries and 10 risk factors, is an example ...
Fibrosis stage is the strongest predictor for disease‐specific mortality in NAFLD after up to 33 years of follow‐up
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the Western world, strongly associated with insulin resistance and the metabolic syndrome. Nonalcoho...
Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory
Alzheimer's disease (AD) and antecedent factors associated with AD were explored using amyloid imaging and unbiased measures of longitudinal atrophy in combination with reanalys...