APE: Analyses of Phylogenetics and Evolution in R language
Abstract Summary: Analysis of Phylogenetics and Evolution (APE) is a package written in the R language for use in molecular evolution and phylogenetics. APE provides both utilit...
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A default mode of brain function
A baseline or control state is fundamental to the understanding of most complex systems. Defining a baseline state in the human brain, arguably our most complex system, poses a ...
Role of Insulin Resistance in Human Disease
Resistance to insulin-stimulated glucose uptake is present in the majority of patients with impaired glucose tolerance (IGT) or non-insulin-dependent diabetes mellitus (NIDDM) a...
The Hungarian method for the assignment problem
Abstract Assuming that numerical scores are available for the performance of each of n persons on each of n jobs, the “assignment problem” is the quest for an assignment of pers...
Absence of Diffusion in Certain Random Lattices
This paper presents a simple model for such processes as spin diffusion or conduction in the "impurity band." These processes involve transport in a lattice which is in some sen...
Scale-space and edge detection using anisotropic diffusion
The scale-space technique introduced by Witkin involves generating coarser resolution images by convolving the original image with a Gaussian kernel. This approach has a major d...
Modularity and community structure in networks
Many networks of interest in the sciences, including social networks, computer networks, and metabolic and regulatory networks, are found to divide naturally into communities or...
A Fast Iterative Shrinkage-Thresholding Algorithm for Linear Inverse Problems
We consider the class of iterative shrinkage-thresholding algorithms (ISTA) for solving linear inverse problems arising in signal/image processing. This class of methods, which ...
Bayes Factors
Abstract In a 1935 paper and in his book Theory of Probability, Jeffreys developed a methodology for quantifying the evidence in favor of a scientific theory. The centerpiece wa...
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene
The HER-2/ neu oncogene is a member of the erb B-like oncogene family, and is related to, but distinct from, the epidermal growth factor receptor. This gene has been shown to be...