Synucleinopathies
The synucleinopathies are a diverse group of neurodegenerative disorders that share a common pathologic lesion composed of aggregates of insoluble alpha-synuclein protein in sel...
Publications
Explore 294 academic publications
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294 publications
Atomic force microscopy and surface-enhanced Raman spectroscopy. I. Ag island films and Ag film over polymer nanosphere surfaces supported on glass
The surface roughness and nanometer scale structure of Ag films used for surface-enhanced Raman scattering (SERS) are characterized using atomic force microscopy (AFM). Two impo...
Quantifying prion disease penetrance using large population control cohorts
Large genomic reference data sets reveal a spectrum of pathogenicity in the prion protein gene and provide genetic validation for a therapeutic strategy in prion disease.
Natural History of Asymptomatic Mitral Valve Prolapse in the Community
Background— The outcome of mitral valve prolapse (MVP) is controversial, with marked discrepancies in reported complication rates. Methods and Results— We conducted a community ...
Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis
Background: There is controversy about the outcome of patients with acute myocarditis (AM), and data are lacking on how patients admitted with suspected AM are managed. We repor...
Surveillance Sans Frontières: Internet-Based Emerging Infectious Disease Intelligence and the HealthMap Project
John Brownstein and colleagues discuss HealthMap, an automated real-time system that monitors and disseminates online information about emerging infectious diseases.
Differential antitumor immunity mediated by NKT cell subsets in vivo
We showed previously that NKT cell–deficient TCR Jα18−/− mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumor surveillance can be restor...
Domain Structure of Rochelle Salt and K<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">H</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>P<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>
It has been verified by means of the polarization microscope that rochelle salt in the ferroelectric state consists of many domains. The domain structure in an annealed crystal ...
Before–after study of a standardized hospital order set for the management of septic shock*
Our study found that the implementation of a standardized order set for the management of septic shock in the emergency department was associated with statistically more rigorou...
Gaussian Process Priors with Uncertain Inputs Application to Multiple-Step Ahead Time Series Forecasting
We consider the problem of multi-step ahead prediction in time series analysis using the non-parametric Gaussian process model. k-step ahead forecasting of a discrete-time non-l...