On the Scientific Evaluation of Diagnostic Procedures
Diagnosis is the cornerstone of modern clinical medicine. It requires accurate observation and rational deduction. In its most complete form it is the process of identifying a d...
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Non‐alcoholic steatohepatitis: What is it, and why is it important in the Asia–Pacific region?
Abstract Non‐alcoholic steatohepatitis (NASH), is a critical link in the chain of metabolic fatty liver disorders that spans steatosis to cryptogenic cirrhosis. It is the hepati...
Direct Liquid Coating of Chalcopyrite Light‐Absorbing Layers for Photovoltaic Devices
Abstract Liquid deposition approaches for chalcopyrite films used in thin‐film photovoltaic devices are reviewed. Most of the targeted materials are based on Cu‐In or Cu‐In‐Ga s...
Impact of cell culture parameters on production and vascularization bioactivity of mesenchymal stem cell‐derived extracellular vesicles
Abstract Mesenchymal stem cell (MSC)‐derived extracellular vesicles (EVs) have emerged as potential therapeutic agents for numerous applications. EVs offer potential advantages ...
Independent prognostic significance of a nuclear proliferation antigen in diffuse large cell lymphomas as determined by the monoclonal antibody Ki-67
Abstract To assess the prognostic significance of the growth fraction in diffuse large cell lymphoma (DLCL), we studied 105 DLCL patients with the monoclonal antibody Ki-67 appl...
Overexpression of <i>NANOG</i> in human ES cells enables feeder-free growth while inducing primitive ectoderm features
Human embryonic stem cells (HESCs) are pluripotent cells derived from the ICM of blastocyst stage embryos. As the factors needed for their growth are largely undefined, they are...
The six-minute walking test in children with cystic fibrosis: Reliability and validity
There is a need to judge general exercise tolerance in children with cystic fibrosis (CF) under normal daily activity conditions and -when more extensive testing is required-in ...
Clonogenic and nonclonogenic in vitro chemosensitivity assays.
We need practical laboratory methods for predicting the chemosensitivity of human neoplasms. Over the past 20 years, numerous investigators have implied or stated with increasin...
Molecular Imaging Using X-Ray Free-Electron Lasers
The opening of hard X-ray free-electron laser facilities, such as the Linac Coherent Light Source (LCLS) at SLAC National Accelerator Laboratory in the United States, has ushere...