Abstract

The opening of hard X-ray free-electron laser facilities, such as the Linac Coherent Light Source (LCLS) at SLAC National Accelerator Laboratory in the United States, has ushered in a new era in structural determination. With X-ray pulse durations down to 10 fs or shorter, and up to 10 13 transversely coherent photons per pulse in a narrow spectral bandwidth, focused irradiances of 10 18 to 10 21 W cm −2 or higher can be produced at X-ray energies ranging from 500 eV to 10 keV. New techniques for determining the structure of systems that cannot be crystallized and for studying the time-resolved behavior of irreversible reactions at femtosecond timescales are now available.

Keywords

LaserMaterials scienceFree electron modelElectronX-rayOpticsPhysicsNuclear physics

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Publication Info

Year
2013
Type
article
Volume
64
Issue
1
Pages
415-435
Citations
186
Access
Closed

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Anton Barty, Jochen Küpper, Henry N. Chapman (2013). Molecular Imaging Using X-Ray Free-Electron Lasers. Annual Review of Physical Chemistry , 64 (1) , 415-435. https://doi.org/10.1146/annurev-physchem-032511-143708

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DOI
10.1146/annurev-physchem-032511-143708