Isolation of a candidate human hematopoietic stem-cell population.
We have identified a rare (0.05-0.1%) subset of human fetal bone marrow cells that contains multipotent hematopoietic precursors. The population of human precursor cells that ex...
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210 publications
Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey
Extracellular vesicles (EVs) represent an important mode of intercellular communication. Research in this field has grown rapidly in the last few years, and there is a plethora ...
Rationale and Standards for the Systematic Review of Qualitative Literature in Health Services Research
Despite growing recognition of the need for qualitative methods in health services research, there have been few attempts to define quality standards for assessing the results. ...
Partitioning Variation in Multilevel Models
Abstract In multilevel modeling the residual variation in a response variable is split into component parts that are attributed to various levels. In applied work, much use is m...
The Galactic Disk Mass Function: Reconciliation of the [ITAL]Hubble Space Telescope[/ITAL] and Nearby Determinations
We derive and parametrize the Galactic mass function (MF) below 1 $\msol$ characteristic of both single objects and binary systems. We resolve the long standing discrepancy betw...
The anatomy of melancholia – focal abnormalities of cerebral blood flow in major depression
Synopsis Using positron emission tomography (PET) and 15 Oxygen, regional cerebral blood flow (rCBF) was measured in 33 patients with primary depression, 10 of whom had an assoc...
Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.
Proteins anchored by GPI are poorly solubilized from cell membranes by cold nonionic detergents because they associate with detergent-resistant membranes rich in cholesterol and...
Control of respiration and ATP synthesis in mammalian mitochondria and cells
We have seen that there is no simple answer to the question ‘what controls respiration?’ The answer varies with (a) the size of the system examined (mitochondria, cell or organ)...
Long-Term Outcomes of Immediate Repair Compared with Surveillance of Small Abdominal Aortic Aneurysms
Among patients with a small abdominal aortic aneurysm, we found no long-term difference in mean survival between the early-surgery and surveillance groups, although after eight ...