Publications

Dimensionality reduction for visualizing single-cell data using UMAP

Surface-enhanced spectroscopy

In 1978 it was discovered, largely through the work of Fleischmann, Van Duyne, Creighton, and their coworkers that molecules adsorbed on specially prepared silver surfaces produ...

Anomalous collapses of Nares Strait ice arches leads to enhanced export of Arctic sea ice

2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

2019 ESC Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases developed in collaboration with the EASD

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

Endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better functional outcomes than s...

Statistical confidence for likelihood‐based paternity inference in natural populations

Paternity inference using highly polymorphic codominant markers is becoming common in the study of natural populations. However, multiple males are often found to be genetically...

Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients

In patients with severe aortic stenosis who were at low surgical risk, TAVR with a self-expanding supraannular bioprosthesis was noninferior to surgery with respect to the compo...

DNA methylation-based classification of central nervous system tumours

Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19), is an emerging health threat.1 Until February 20...

Transcriptome and genome sequencing uncovers functional variation in humans

Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, Canadian Stroke Network, Health Research Board Ireland, Swedish Research Council, Swedish Heart an...

The landscape of cancer genes and mutational processes in breast cancer

All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer clonal selective advantage on cancer cells and are causally implicated in oncog...