Publications

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

Paradoxical roles of the immune system during cancer development

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...

A Whole-Genome Assembly of <i>Drosophila</i>

We report on the quality of a whole-genome assembly of Drosophila melanogaster and the nature of the computer algorithms that accomplished it. Three independent external data so...

A large-scale evaluation of computational protein function prediction

The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

B-cell-derived lymphotoxin promotes castration-resistant prostate cancer

FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis

Public health impacts of the severe haze in Equatorial Asia in September–October 2015: demonstration of a new framework for informing fire management strategies to reduce downwind smoke exposure

In September–October 2015, El Niño and positive Indian Ocean Dipole conditions set the stage for massive fires in Sumatra and Kalimantan (Indonesian Borneo), leading to persiste...

Consistent Partial Least Squares for Nonlinear Structural Equation Models

Partial Least Squares as applied to models with latent variables, measured indirectly by indicators, is well-known to be inconsistent. The linear compounds of indicators that PL...

Relationship of Anxiety and Depression with Respiratory Symptoms: Comparison between Depressed and Non-Depressed Smokers in Singapore

The rising prevalence of smokers in the community, specifically psychiatric patients, necessitates smoking cessation as an important strategy for reducing the harmful effects of...