Publications
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Ditching Invading DNA Bacteria and archaea protect themselves from invasive foreign nucleic acids through an RNA-mediated adaptive immune system called CRISPR (clustered regular...
GENEPOP (Version 1.2): Population Genetics Software for Exact Tests and Ecumenicism
Journal Article GENEPOP (Version 1.2): Population Genetics Software for Exact Tests and Ecumenicism Get access M. Raymond, M. Raymond Institut des Sciences de l'Evolution, URA C...
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
<b><i>Background:</i></b> Cancer immunotherapy, such as anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1 (PD-1), has...
UCHIME improves sensitivity and speed of chimera detection
Abstract Motivation: Chimeric DNA sequences often form during polymerase chain reaction amplification, especially when sequencing single regions (e.g. 16S rRNA or fungal Interna...
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older. Safety over a median of 2 months was similar to that of other viral...
Tissue-based map of the human proteome
Protein expression across human tissues Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic exp...
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma. Adverse eve...
Monte Carlo sampling methods using Markov chains and their applications
A generalization of the sampling method introduced by Metropolis et al. (1953) is presented along with an exposition of the relevant theory, techniques of application and method...
The 1982 revised criteria for the classification of systemic lupus erythematosus
Abstract The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve...