Abstract
Blood group antigens of erythrocytes have been studied by the fluorescent antibody technique (1, 2), but their size, shape, and distribution have not been analyzed by this method. With the advent of ferritin-labeled globulins, it has been possible to identify and locate specific antigens of bacteria (3), viruses (4), tumor cells (5), erythrocytes (6, 7), and injurious molecular complexes causing tissue injury (8, 9). This report demonstrates the site and distribution of type A and type Rho (D) antigens in human red cells using ferritin conjugated to immune globulins.
Keywords
BiologyFerritinAntigenAntibodyConjugateEpitopeVirologyComputational biologyImmunologyBiochemistry
MeSH Terms
AntibodiesAntigensCell BiologyElectronsErythrocytesFerritinsHumansMicroscopyMicroscopyElectronResearchRh-Hr Blood-Group SystemSerum Globulins
Affiliated Institutions
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Publication Info
- Year
- 1964
- Type
- article
- Volume
- 23
- Issue
- 2
- Pages
- 396-400
- Citations
- 70
- Access
- Closed
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Cite This
Robert Lee,
Joseph D. Feldman
(1964).
VISUALIZATION OF ANTIGENIC SITES OF HUMAN ERYTHROCYTES WITH FERRITIN-ANTIBODY CONJUGATES.
The Journal of Cell Biology
, 23
(2)
, 396-400.
https://doi.org/10.1083/jcb.23.2.396
Identifiers
- DOI
- 10.1083/jcb.23.2.396
- PMID
- 14222824
- PMCID
- PMC2106533