Trial of Early, Goal-Directed Resuscitation for Septic Shock

Abstract

In patients with septic shock who were identified early and received intravenous antibiotics and adequate fluid resuscitation, hemodynamic management according to a strict EGDT protocol did not lead to an improvement in outcome. (Funded by the United Kingdom National Institute for Health Research Health Technology Assessment Programme; ProMISe Current Controlled Trials number, ISRCTN36307479.).

Keywords

MedicineEarly goal-directed therapyResuscitationSeptic shockRandomized controlled trialRelative riskIntensive care unitShock (circulatory)Confidence intervalIntensive care medicineAdverse effectEmergency medicineSepsisInternal medicine

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Publication Info

Year: 2015
Type: article
Volume: 372
Issue: 14
Pages: 1301-1311
Citations: 1522
Access: Closed

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APA Style

                            
                                
                                    Paul Mouncey, 
                                
                                    Tiffany M. Osborn, 
                                
                                    G. Sarah Power
                                
                                et al.
                            
                            (2015). 
                            Trial of Early, Goal-Directed Resuscitation for Septic Shock. 
                            New England Journal of Medicine
                            , 372
                            (14)
                            , 1301-1311.
                            https://doi.org/10.1056/nejmoa1500896
                        

Identifiers

DOI: 10.1056/nejmoa1500896