Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol*

Abstract

Clinical implementation of a comprehensive sepsis treatment protocol is feasible and is associated with changes in therapies such as time to antibiotics, intravenous fluid delivery, and vasopressor use in the first 6 hrs. No statistically significant decrease in mortality was demonstrated, as this trial was not sufficiently powered to assess mortality benefits.

Keywords

MedicineSeptic shockEmergency departmentSepsisIntensive care unitSurviving Sepsis CampaignEmergency medicineIntensive careDrotrecogin alfaProspective cohort studyEarly goal-directed therapyIntensive care medicineInternal medicineSevere sepsis

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Publication Info

Year: 2006
Type: article
Volume: 34
Issue: 4
Pages: 1025-1032
Citations: 353
Access: Closed

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APA Style

                            
                                
                                    Nathan I. Shapiro, 
                                
                                    Michael D. Howell, 
                                
                                    Daniel Talmor
                                
                                et al.
                            
                            (2006). 
                            Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol*. 
                            Critical Care Medicine
                            , 34
                            (4)
                            , 1025-1032.
                            https://doi.org/10.1097/01.ccm.0000206104.18647.a8
                        

Identifiers

DOI: 10.1097/01.ccm.0000206104.18647.a8