Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery

2010 New England Journal of Medicine 6,968 citations

Abstract

In patients with severe aortic stenosis who were not suitable candidates for surgery, TAVI, as compared with standard therapy, significantly reduced the rates of death from any cause, the composite end point of death from any cause or repeat hospitalization, and cardiac symptoms, despite the higher incidence of major strokes and major vascular events. (Funded by Edwards Lifesciences; ClinicalTrials.gov number, NCT00530894.).

Keywords

MedicineStenosisAortic valve replacementCardiologyInternal medicineAortic valve stenosisAortic valveSurgery

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Publication Info

Year
2010
Type
article
Volume
363
Issue
17
Pages
1597-1607
Citations
6968
Access
Closed

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Martin B. Leon, Craig R. Smith, Michael J. Mack et al. (2010). Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery. New England Journal of Medicine , 363 (17) , 1597-1607. https://doi.org/10.1056/nejmoa1008232

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DOI
10.1056/nejmoa1008232