Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

Abstract

Among patients with severe aortic stenosis who were at low surgical risk, the rate of the composite of death, stroke, or rehospitalization at 1 year was significantly lower with TAVR than with surgery. (Funded by Edwards Lifesciences; PARTNER 3 ClinicalTrials.gov number, NCT02675114.).

Keywords

MedicineValve replacementStenosisAortic valve replacementCardiologyInternal medicineAortic valve stenosisBalloonSurgeryAortic valve

Affiliated Institutions

Related Publications

Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients

Jeffrey J. Popma , G. Michael Deeb , Steven J. Yakubov +28 more

In patients with severe aortic stenosis who were at low surgical risk, TAVR with a self-expanding supraannular bioprosthesis was noninferior to surgery with respect to the compo...

2019 New England Journal of Medicine 3394 citations

Pathophysiology of Valvular Aortic Stenois in the Elderly

Melvin D. Cheitlin

Aortic stenosis in the elderly is related to calcification of either a bicuspid valve or a morphologically normal tricuspid valve. There is increasing evidence that factors rela...

2003 The American Journal of Geriatric Car... 13 citations

Sex Differences in Morphology and Outcomes of Mitral Valve Prolapse

Jean-François Aviérinos , Jocelyn Inamo , Francesco Grigioni +3 more

Morphology and severity of mitral valve prolapse differ according to sex. Among patients with severe regurgitation, women have higher mortality and lower surgery rates than men.

2008 Annals of Internal Medicine 195 citations

Influence of sex on expansion rate of abdominal aortic aneurysms

Reza Mofidi , V.J. Goldie , J.A. Kelman +3 more

Abstract Background The UK Small Aneurysm Trial suggested that female sex is an independent risk factor for rupture of abdominal aortic aneurysm (AAA). This study assessed the e...

2007 British journal of surgery 141 citations

Publication Info

Year: 2019
Type: article
Volume: 380
Issue: 18
Pages: 1695-1705
Citations: 4463
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

4463

OpenAlex

Cite This

APA Style

                            
                                
                                    Michael J. Mack, 
                                
                                    Martin B. Leon, 
                                
                                    Vinod H. Thourani
                                
                                et al.
                            
                            (2019). 
                            Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients. 
                            New England Journal of Medicine
                            , 380
                            (18)
                            , 1695-1705.
                            https://doi.org/10.1056/nejmoa1814052
                        

Identifiers

DOI: 10.1056/nejmoa1814052