Keywords
Cell biologyImmune systemToll-like receptorHMGB1ReceptorSignal transductionEndoplasmic reticulumCD14BiologyInnate immune systemImmunologyBiochemistry
Affiliated Institutions
Related Publications
Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency
Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share an intracytoplasmic Toll–IL-1 receptor (TIR) domain, which mediates recruitment of t...
Cutting Edge: Recognition of Gram-Positive Bacterial Cell Wall Components by the Innate Immune System Occurs Via Toll-Like Receptor 2
Abstract Invasive infection with Gram-positive and Gram-negative bacteria often results in septic shock and death. The basis for the earliest steps in innate immune response to ...
A family of human receptors structurally related to <i>Drosophila</i> Toll
The discovery of sequence homology between the cytoplasmic domains of Drosophila Toll and human interleukin 1 receptors has sown the conviction that both molecules trigger relat...
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
Recognition by innate immune cells of the pathogen associated molecular patterns (PAMP) lipopolysaccharide (LPS) from Gram-negative bacteria and bacterial CpG-DNA depends on Tol...
Toll-Like Receptors
The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defen...
Publication Info
- Year
- 2008
- Type
- review
- Volume
- 20
- Issue
- 4
- Pages
- 420-425
- Citations
- 207
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
207
OpenAlex
Cite This
Sachiko Akashi‐Takamura,
Kensuke Miyake
(2008).
TLR accessory molecules.
Current Opinion in Immunology
, 20
(4)
, 420-425.
https://doi.org/10.1016/j.coi.2008.07.001
Identifiers
- DOI
- 10.1016/j.coi.2008.07.001