Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

Keywords

Drosophila melanogasterUbiquitinRegulatorCell biologyCell fate determinationHippo signaling pathwayBiologyProtein degradationCell growthSignal transductionBiochemistryTranscription factorGene

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Publication Info

Year
1992
Type
review
Volume
61
Issue
1
Pages
761-807
Citations
1413
Access
Closed

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Cite This

A Hershko, Aaron Ciechanover (1992). THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION. Annual Review of Biochemistry , 61 (1) , 761-807. https://doi.org/10.1146/annurev.bi.61.070192.003553

Identifiers

DOI
10.1146/annurev.bi.61.070192.003553