Keywords
Affiliated Institutions
Related Publications
Amyloids protect the silkmoth oocyte and embryo
Chorion is the major component of silkmoth eggshell. More than 95% of its dry mass consists of proteins that have remarkable mechanical and chemical properties protecting the oo...
Protein fibrils in nature can enhance amyloid protein A amyloidosis in mice: Cross-seeding as a disease mechanism
Secondary, or amyloid protein A (AA), amyloidosis is a complication of chronic inflammatory diseases, both infectious and noninfectious. AA constitutes the insoluble fibrils, wh...
The formation of spherulites by amyloid fibrils of bovine insulin
Bovine insulin has long been known to self-assemble in vitro into amyloid fibrils. We have observed a further higher-order self-association of the protein into spherical structu...
Structural Characterization of the Fibrillar Form of the Yeast <i>Saccharomyces cerevisiae</i> Prion Ure2p
The protein Ure2 from the yeast Saccharomyces cerevisiae has prion properties. It assembles in vitro into long, straight, insoluble fibrils that are similar to amyloids in that ...
A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain‐derived synaptic plasticity‐disrupting Aβ
J. Neurochem. (2011) 119 , 189–201. Abstract Diverse lines of evidence indicate that pre‐fibrillar, diffusible assemblies of the amyloid β‐protein (Aβ) play an important role in...
Publication Info
- Year
- 1997
- Type
- review
- Volume
- 50
- Pages
- 123-159
- Citations
- 748
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1016/s0065-3233(08)60320-4