The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

Daniel I. Swerdlow , Michael V. Holmes , Karoline Kuchenbaecker , Daniel I. Swerdlow , Michael V. Holmes , Karoline Kuchenbaecker , Jorgen Engmann , Tina Shah , Reecha Sofat , Yiran Guo , Christina Lee Chung , Anne Peasey , R Pfister , Simon P. Mooijaart , Helen Ireland , Maarten Leusink , Claudia Langenberg , Ka Wan Li , Jutta Palmen , Philip Howard , Jackie A. Cooper , Fotios Drenos , John Hardy , Michael A. Nalls , Leslie A. Lange , Gordon Lowe , Marlene Stewart , Suzette J. Bielinski , Julian Peto , Nicholas J. Timpson , J.E.J. Gallacher , Malcolm G. Dunlop , Richard S. Houlston , Ian Tomlinson , Ioanna Tzoulaki , Jian’an Luan , Boer Jma. , Nita G. Forouhi , N. Charlotte Onland‐Moret , Yvonne T. van der Schouw , Renate B. Schnabel , Jaroslav A. Hubáček , Růžena Kubínová , Miglė Bacevičienė , Abdonas Tamošiūnas , Andrzej Pająk , R Topor-Madry , Sofia Malyutina , Damiano Baldassarre , Bengt Sennblad , Elena Tremoli , Ulf dé Fairé , Luigi Ferrucci , S Bandenelli , Toshiko Tanaka , James F. Meschia , Andrew Singleton , Gerjan Navis , Irene Mateo Leach , Bakker Sjl. , Ron T. Gansevoort , Ian Ford , Stephen E. Epstein , Mary Susan Burnett , Joseph M. Devaney , J. Wouter Jukema , Westendorp Rgj. , Gert J. de Borst , Yolanda van der Graaf , Pim A. de Jong , Mailand-van der Zee A-H. , Olaf H. Klungel , Anthonius de Boer , Pieter A. Doevendans , James M. Stephens , Charles B. Eaton , Jennifer G. Robinson , JoAnn E. Manson , F. Gerry R. Fowkes , Timothy M. Frayling , Jackie F. Price , Peter H. Whincup , Richard Morris , Debbie A. Lawlor , George Davey Smith , Yoav Ben‐Shlomo , Susan Redline , Leslie A. Lange , Meena Kumari , Nicholas J. Wareham , Verschuren Wmm , Emelia J. Benjamin , John C. Whittaker , Anders Hamsten , Frank Dudbridge , Joseph A. Delaney , Andrew Wong , Diana Kuh , Rebecca Hardy , Brianna Castillo , John J. Connolly , Pim van der Harst , Eric J. Brunner
2012 The Lancet 1,103 citations

Keywords

MedicineRheumatoid arthritisTocilizumabSingle-nucleotide polymorphismInternal medicineOdds ratioArthritisMendelian randomizationSNPGastroenterologyGenotypeBiologyGene

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Publication Info

Year
2012
Type
review
Volume
379
Issue
9822
Pages
1214-1224
Citations
1103
Access
Closed

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Daniel I. Swerdlow, Michael V. Holmes, Karoline Kuchenbaecker et al. (2012). The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. The Lancet , 379 (9822) , 1214-1224. https://doi.org/10.1016/s0140-6736(12)60110-x

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DOI
10.1016/s0140-6736(12)60110-x