Abstract

Outcome reporting bias is an under-recognised problem that affects the conclusions in a substantial proportion of Cochrane reviews. Individuals conducting systematic reviews need to address explicitly the issue of missing outcome data for their review to be considered a reliable source of evidence. Extra care is required during data extraction, reviewers should identify when a trial reports that an outcome was measured but no results were reported or events observed, and contact with trialists should be encouraged.

Keywords

MedicineSystematic reviewOutcome (game theory)Reporting biasMeta-analysisClinical trialMEDLINEMissing dataPublication biasCohortCohort studySelection biasPediatricsInternal medicineFamily medicinePathologyStatistics

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Year
2010
Type
article
Volume
340
Issue
feb15 1
Pages
c365-c365
Citations
1110
Access
Closed

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Jamie J Kirkham, Kerry Dwan, Doug Altman et al. (2010). The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ , 340 (feb15 1) , c365-c365. https://doi.org/10.1136/bmj.c365

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DOI
10.1136/bmj.c365