The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

Hiroshi Maeda; Hideaki Nakamura; Jun Fang

doi:10.1016/j.addr.2012.10.002

Keywords

ExtravasationIn vivoDrug deliveryToxicityPharmacologyDrugChemistryMedicineElectron paramagnetic resonanceCancer researchPathologyInternal medicineNuclear magnetic resonanceBiology

Affiliated Institutions

Sojo University JP

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Publication Info

Year: 2012
Type: review
Volume: 65
Issue: 1
Pages: 71-79
Citations: 2280
Access: Closed

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APA Style

                            
                                    Hiroshi Maeda, 
                                
                                    Hideaki Nakamura, 
                                
                                    Jun Fang
                                
                            (2012). 
                            The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo. 
                            Advanced Drug Delivery Reviews
                            , 65
                            (1)
                            , 71-79.
                            https://doi.org/10.1016/j.addr.2012.10.002

Identifiers

DOI: 10.1016/j.addr.2012.10.002