Abstract

Recently, iron oxide nanoparticles (NPs) have attracted much consideration due to their unique properties, such as superparamagnetism, surface-to-volume ratio, greater surface area, and easy separation methodology. Various physical, chemical, and biological methods have been adopted to synthesize magnetic NPs with suitable surface chemistry. This review summarizes the methods for the preparation of iron oxide NPs, size and morphology control, and magnetic properties with recent bioengineering, commercial, and industrial applications. Iron oxides exhibit great potential in the fields of life sciences such as biomedicine, agriculture, and environment. Nontoxic conduct and biocompatible applications of magnetic NPs can be enriched further by special surface coating with organic or inorganic molecules, including surfactants, drugs, proteins, starches, enzymes, antibodies, nucleotides, nonionic detergents, and polyelectrolytes. Magnetic NPs can also be directed to an organ, tissue, or tumor using an external magnetic field for hyperthermic treatment of patients. Keeping in mind the current interest in iron NPs, this review is designed to report recent information from synthesis to characterization, and applications of iron NPs.

Keywords

NanotechnologySuperparamagnetismIron oxide nanoparticlesIron oxideNanoparticleMagnetic nanoparticlesMaterials scienceSurface modificationCharacterization (materials science)Chemical engineeringMagnetizationMagnetic fieldMetallurgy

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Publication Info

Year
2016
Type
review
Volume
Volume 9
Pages
49-67
Citations
1464
Access
Closed

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1464
OpenAlex
33
Influential
1356
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Cite This

Attarad Ali, Hira Zafar, Muhammad Zia et al. (2016). Synthesis, characterization, applications, and challenges of iron oxide nanoparticles. Nanotechnology Science and Applications , Volume 9 , 49-67. https://doi.org/10.2147/nsa.s99986

Identifiers

DOI
10.2147/nsa.s99986
PMID
27578966
PMCID
PMC4998023

Data Quality

Data completeness: 81%