Abstract

Biocompatible magnetite nanocrystals (see Figure) are prepared by thermal decomposition of ferric triacetylacetonate in 2-pyrrolidone in the presence of monocarboxyl-terminated poly(ethylene glycol) (MPEG-COOH). The results reveal that MPEG is covalently bound to the nanocrystal surface by COOH groups. Magnetic resonance imaging (MRI) experiments indicate that the coated nanocrystals are potential MRI contrast agents due to their excellent water solubility and biocompatibility.

Keywords

Biocompatible materialMaterials scienceMagnetite NanoparticlesMagnetiteNanoparticleNanotechnologyChemical engineeringMagnetic nanoparticlesMetallurgyBiomedical engineering

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Publication Info

Year
2005
Type
article
Volume
17
Issue
8
Pages
1001-1005
Citations
493
Access
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Li Zhu, Li Wei, Mingyuan Gao et al. (2005). One‐Pot Reaction to Synthesize Biocompatible Magnetite Nanoparticles. Advanced Materials , 17 (8) , 1001-1005. https://doi.org/10.1002/adma.200401545

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DOI
10.1002/adma.200401545