Abstract

Unlike the CSF biomarkers evaluated, changes in serial structural MRI are correlated with concurrent change on general cognitive and functional indices in impaired subjects, track with clinical disease stage, and are influenced by APOE genotype.

Keywords

BiomarkerMedicineNeuroimagingInternal medicineClinical trialImaging biomarkerAlzheimer's diseaseCerebrospinal fluidBrain sizeCorrelationCardiologyMagnetic resonance imagingPsychologyOncologyPathologyDiseaseRadiologyPsychiatry

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Publication Info

Year
2010
Type
article
Volume
75
Issue
2
Pages
143-151
Citations
161
Access
Closed

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Prashanthi Vemuri, H. Wiste, Stephen D. Weigand et al. (2010). Serial MRI and CSF biomarkers in normal aging, MCI, and AD. Neurology , 75 (2) , 143-151. https://doi.org/10.1212/wnl.0b013e3181e7ca82

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DOI
10.1212/wnl.0b013e3181e7ca82