Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

Pedro M. Folegatti , Katie Ewer , Parvinder K. Aley , Pedro M. Folegatti , Katie Ewer , Parvinder K. Aley , Brian Angus , Stephan Becker , Sandra Belij‐Rammerstorfer , Duncan Bellamy , Sagida Bibi , Mustapha Bittaye , Elizabeth Clutterbuck , Christina Dold , Saul N. Faust , Adam Finn , Amy Flaxman , Bassam Hallis , Paul T. Heath , Daniel Jenkin , Rajeka Lazarus , Rebecca Makinson , Angela M. Minassian , Katrina M. Pollock , Maheshi Ramasamy , Hannah Robinson , Matthew D. Snape , Richard Tarrant , Merryn Voysey , Catherine Green , Alexander D. Douglas , Adrian V. S. Hill , Teresa Lambe , Sarah C. Gilbert , Andrew J. Pollard , Jeremy Aboagye , K. F. Adams , Aabidah Ali , Elizabeth Allen , Jennifer L. Allison , Rachel Anslow , Edward H. Arbe-Barnes , Gavin Babbage , J. Kenneth Baillie , Megan Baker , Natalie Baker , Philip Baker , Ioana Baleanu , Juliana Ballaminut , Eleanor Barnes , Jordan R. Barrett , Louise Bates , Alexander Batten , Kirsten Beadon , Rebecca Beckley , Eleanor Berrie , Lisa Berry , Amy Beveridge , Kevin R. Bewley , Else M. Bijker , Tracey Bingham , Luke Blackwell , Caitlin L. Blundell , Emma Bolam , Elena Boland , Nicola Borthwick , Thomas Bower , Amy Boyd , Tanja Brenner , Philip Bright , Charlie Brown-O’Sullivan , Emily Brunt , Jamie Burbage , Sharon Burge , Karen R. Buttigieg , Nicholas Byard , Ingrid Cabera Puig , Anna Calvert , Susana Camara , Michelangelo Cao , Federica Cappuccini , Melanie Carr , Miles W. Carroll , Victoria Carter , Katrina Cathie , Ruth Challis , Sue Charlton , Irina Chelysheva , Jee-Sun Cho , Paola Cicconi , Liliana Cifuentes , Helen Clark , Elizabeth Clark , Tom Cole , Rachel Colin-Jones , Christopher P. Conlon , Aislinn Cook , Naomi S. Coombes , Rachel Cooper , Catherine A. Cosgrove , Karen Coy , Wendy E.M. Crocker , Christina J. Cunningham
2020 The Lancet 2,590 citations

Keywords

ReactogenicityImmunogenicityMedicineVaccinationNeutralizationVirologyPlaque reduction neutralization testVaccination scheduleImmunologyCoronavirusRandomized controlled trialInternal medicineAntibodyCoronavirus disease 2019 (COVID-19)Immunization

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Year
2020
Type
article
Volume
396
Issue
10249
Pages
467-478
Citations
2590
Access
Closed

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Pedro M. Folegatti, Katie Ewer, Parvinder K. Aley et al. (2020). Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial. The Lancet , 396 (10249) , 467-478. https://doi.org/10.1016/s0140-6736(20)31604-4

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DOI
10.1016/s0140-6736(20)31604-4