Keywords
Nitric oxideMacrophageAntimicrobialEffectorCitrullineNitric oxide synthaseReactive nitrogen speciesMicrobiologyChemistryBiochemistryArginineImmunologyBiologyIn vitro
Affiliated Institutions
Related Publications
NITRERGIC TRANSMISSION: NITRIC OXIDE AS A MEDIATOR OF NON‐ADRENERGIC, NON‐CHOLINERGIC NEURO‐EFFECTOR TRANSMISSION
SUMMARY 1. The possibility that transmission at some non‐adrenergic, non‐cholinergic (NANC) neuro‐effector junctions is mediated by nitric oxide (NO) arose from the discoveries ...
Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate
Previous studies have shown that murine macrophages immunostimulated with interferon gamma and Escherichia coli lipopolysaccharide synthesize NO2-, NO3-, and citrulline from L-a...
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.
This study examined the contribution of nitric oxide (NO) to the susceptibility or resistance to the hypertensive effects of high sodium chloride (8.0% NaCl) intake in young Dah...
Cellular mechanisms of atherogenesis and the effects of nitric oxide
The cellular mechanisms leading to atherosclerosis are becoming more clearly defined. In response to hypercholesterolemia, an endothelial alteration or dysfunction occurs that p...
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.
A soluble enzyme obtained from rat forebrain catalyzes the NADPH-dependent formation of nitric oxide (NO) and citrulline from L-arginine. The NO formed stimulates the soluble gu...
Publication Info
- Year
- 1991
- Type
- review
- Volume
- 3
- Issue
- 1
- Pages
- 65-70
- Citations
- 1530
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
1530
OpenAlex
Cite This
Carl Nathan,
John B. Hibbs
(1991).
Role of nitric oxide synthesis in macrophage antimicrobial activity.
Current Opinion in Immunology
, 3
(1)
, 65-70.
https://doi.org/10.1016/0952-7915(91)90079-g
Identifiers
- DOI
- 10.1016/0952-7915(91)90079-g