Requirement for Wnt3 in vertebrate axis formation

Keywords

EpiblastPrimitive streakGastrulationEndodermBiologyMesodermNODALEctodermHistogenesisAnatomyCell biologyGerm layerBrachyuryLateral plate mesodermNeuroectodermNodal signalingIngressionEmbryogenesisGeneticsEmbryoEmbryonic stem cellImmunology

Affiliated Institutions

Related Publications

The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

Ethan A. Carver , Rulang Jiang , Yu Lan +2 more

Snail family genes encode DNA binding zinc finger proteins that act as transcriptional repressors. Mouse embryos deficient for the Snail (Sna) gene exhibit defects in the format...

2001 Molecular and Cellular Biology 615 citations

<i>nodal</i> expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

Isabelle Varlet , Jérôme Collignon , Elizabeth J. Robertson

ABSTRACT Mouse nodal, a member of the TGFβ family of secreted growth factors is essential for gastrulation. We recently generated a nodallacZ reporter allele by homologous recom...

1997 Development 385 citations

Misexpression of <i>Cwnt8C</i> in the mouse induces an ectopic embryonic axis and causes a truncation of the anterior neuroectoderm

Heike Pöpperl , Christel Schmidt , Valerie Wilson +4 more

ABSTRACT Transgenic embryos expressing Cwnt8C under the control of the human β-actin promoter exhibit duplicated axes or a severely dorsalised phenotype. Although the transgene ...

1997 Development 145 citations

Misexpression of chick Vg1 in the marginal zone induces primitive streak formation

Shailan B. Shah , Isaac Skromne , Clifford R. Hume +4 more

ABSTRACT In the chick embryo, the primitive streak is the first axial structure to develop. The initiation of primitive streak formation in the posterior area pellucida is influ...

1997 Development 121 citations

Nodal signaling and the evolution of deuterostome gastrulation

Helen Chea , Christopher V.E. Wright , Billie J. Swalla

Abstract Chordates, including vertebrates, evolved within a group of animals called the deuterostomes. All holoblastic deuterostomes gastrulate at the vegetal pole and the blast...

2005 Developmental Dynamics 108 citations

Publication Info

Year: 1999
Type: article
Volume: 22
Issue: 4
Pages: 361-365
Citations: 892
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Requirement for Wnt3 in vertebrate axis formation

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

892

OpenAlex

Cite This

APA Style

                            
                                
                                    Pentao Liu, 
                                
                                    Maki Wakamiya, 
                                
                                    Martin J. Shea
                                
                                et al.
                            
                            (1999). 
                            Requirement for Wnt3 in vertebrate axis formation. 
                            Nature Genetics
                            , 22
                            (4)
                            , 361-365.
                            https://doi.org/10.1038/11932
                        

Identifiers

DOI: 10.1038/11932