Physical Properties of a Genomic Condensed Chromatin Fragment

Rodolfo Ghirlando; Michael D. Litt; Marie‐Noëlle Prioleau; Félix Recillas‐Targa; Gary Felsenfeld

doi:10.1016/j.jmb.2003.12.049

Keywords

Sedimentation coefficientChromatinHomogeneity (statistics)UltracentrifugeHomogeneousChemistryParticle (ecology)Locus (genetics)BiophysicsDNAPhysicsChromatographyBiologyEnzymeBiochemistryGeneThermodynamicsMathematics

Affiliated Institutions

Related Publications

SUPERCOILED CIRCULAR DNA-PROTEIN COMPLEX IN <i>Escherichia coli</i> : PURIFICATION AND INDUCED CONVERSION TO AN OPEN CIRCULAR DNA FORM

Don B. Clewell , Donald R. Helinski

The 23 S twisted circular form of Col E 1 DNA has been isolated from Escherichia coli as a tightly associated DNA-protein complex with a sedimentation coefficient of approximate...

1969 Proceedings of the National Academy o... 1818 citations

Removal of RNase activity from DNase by affinity chromatography on agarose-coupled aminophenylphosphoryl-uridlne-2′(3′)-phosphate

Ian H. Maxwell , F Maxwell , William E. Hahn

Severe degradation of high molecular weight RNA was shown to occur during incubation with commercially purified DNase. Most of the RNase activity could be removed by passage of ...

1977 Nucleic Acids Research 98 citations

Spatially confined folding of chromatin in the interphase nucleus

Julio Mateos‐Langerak , Manfred Bohn , Wim de Leeuw +8 more

Genome function in higher eukaryotes involves major changes in the spatial organization of the chromatin fiber. Nevertheless, our understanding of chromatin folding is remarkabl...

2009 Proceedings of the National Academy o... 250 citations

Defining the Sequence Specificity of DNA-Binding Proteins by Selecting Binding Sites from Random-Sequence Oligonucleotides: Analysis of Yeast GCN4 Protein

Arnold Oliphant , Christopher J. Brandl , Kevin Struhl

We describe a new method for accurately defining the sequence recognition properties of DNA-binding proteins by selecting high-affinity binding sites from random-sequence DNA. T...

1989 Molecular and Cellular Biology 339 citations

Interpreting non-coding variation in complex disease genetics

Lucas D. Ward , Manolis Kellis

Association studies provide genome-wide information about the genetic basis of complex disease, but medical research has primarily focused on protein-coding variants, due to the...

2012 DSpace@MIT (Massachusetts Institute o... 511 citations

Publication Info

Year: 2004
Type: article
Volume: 336
Issue: 3
Pages: 597-605
Citations: 41
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Physical Properties of a Genomic Condensed Chromatin Fragment

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                
                                    Rodolfo Ghirlando, 
                                
                                    Michael D. Litt, 
                                
                                    Marie‐Noëlle Prioleau
                                
                                et al.
                            
                            (2004). 
                            Physical Properties of a Genomic Condensed Chromatin Fragment. 
                            Journal of Molecular Biology
                            , 336
                            (3)
                            , 597-605.
                            https://doi.org/10.1016/j.jmb.2003.12.049
                        

Identifiers

DOI: 10.1016/j.jmb.2003.12.049