On/off blinking and switching behaviour of single molecules of green fluorescent protein

Robert M. Dickson; A B Cubitt; Roger Y. Tsien; W. E. Moerner

doi:10.1038/41048

Keywords

FluorescenceGreen fluorescent proteinBiophysicsChemistryFluorescent proteinNanotechnologyMaterials scienceBiologyBiochemistryPhysicsOpticsGene

Affiliated Institutions

University of California, San Diego US

Related Publications

Alterations of Single Molecule Fluorescence Lifetimes in Near-Field Optical Microscopy

W. Patrick Ambrose , Peter M. Goodwin , Richard A. Keller +1 more

Fluorescence lifetimes of single Rhodamine 6G molecules on silica surfaces were measured with pulsed laser excitation, time-correlated single photon counting, and near-field sca...

1994 Science 339 citations

Advances in fluorescent protein technology

Nathan C. Shaner , George H. Patterson , Michael W. Davidson

Current fluorescent protein (FP) development strategies are focused on fine-tuning the photophysical properties of blue to yellow variants derived from the Aequorea victoria jel...

2007 Journal of Cell Science 759 citations

Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo

Daniel R. Larson , Warren R. Zipfel , Rebecca M. Williams +4 more

The use of semiconductor nanocrystals (quantum dots) as fluorescent labels for multiphoton microscopy enables multicolor imaging in demanding biological environments such as liv...

2003 Science 2263 citations

Imaging of single molecule diffusion.

Thomas Schmidt , Gerhard J. Schütz , Werner Baumgärtner +2 more

In recent years observations at the level of individual atoms and molecules became possible by microscopy and spectroscopy. Imaging of single fluorescence molecules has been ach...

1996 Proceedings of the National Academy o... 616 citations

Properties of Fluorescent Semiconductor Nanocrystals and their Application to Biological Labeling

Xavier Michalet , Fabien Pinaud , Thilo D. Lacoste +4 more

We review recent advances in the development of colloidal fluorescent semiconductor nanocrystals (a class of quantum dots) for biological labeling. Although some of the photophy...

2001 Single Molecules 366 citations

Publication Info

Year: 1997
Type: article
Volume: 388
Issue: 6640
Pages: 355-358
Citations: 1331
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

On/off blinking and switching behaviour of single molecules of green fluorescent protein

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1331

OpenAlex

Cite This

APA Style

                            
                                
                                    Robert M. Dickson, 
                                
                                    A B Cubitt, 
                                
                                    Roger Y. Tsien
                                
                                et al.
                            
                            (1997). 
                            On/off blinking and switching behaviour of single molecules of green fluorescent protein. 
                            Nature
                            , 388
                            (6640)
                            , 355-358.
                            https://doi.org/10.1038/41048
                        

Identifiers

DOI: 10.1038/41048