Abstract

Three-month-old rats were injected intraperitoneally with [ 3 H]thymidine (4.3 microcuries per gram of body weight) and allowed to survive for 30 days. Radioautography of 1-μm sections revealed labeled cells in the granular layers of dentate gyrus and olfactory bulb; these were confirmed as neurons by electron microscopy of reembedded 1-μm sections.

Keywords

NeurogenesisOlfactory bulbDentate gyrusElectron microscopeThymidineBiologyChemistryBiophysicsAnatomyPathologyHippocampusCell biologyNeurosciencePhysicsBiochemistryMedicineCentral nervous systemOpticsDNA

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Publication Info

Year
1977
Type
article
Volume
197
Issue
4308
Pages
1092-1094
Citations
1440
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Closed

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Michael Kaplan, James W. Hinds (1977). Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light Radioautographs. Science , 197 (4308) , 1092-1094. https://doi.org/10.1126/science.887941

Identifiers

DOI
10.1126/science.887941