Abstract

Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The emergence of SARS-CoV-2 has been marked as the third introduction of a highly pathogenic coronavirus into the human population after the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) in the twenty-first century. In this minireview, we provide a brief introduction of the general features of SARS-CoV-2 and discuss current knowledge of molecular immune pathogenesis, diagnosis and treatment of COVID-19 on the base of the present understanding of SARS-CoV and MERS-CoV infections, which may be helpful in offering novel insights and potential therapeutic targets for combating the SARS-CoV-2 infection.

Keywords

Middle East respiratory syndrome coronavirusCoronavirusPathogenesisSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PneumoniaCoronavirus disease 2019 (COVID-19)Immune systemVirologyDiseasePopulationImmunologyAtypical pneumoniaSevere acute respiratory syndromeBetacoronavirusMedicineInfectious disease (medical specialty)Pathology

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Publication Info

Year
2020
Type
review
Volume
10
Issue
2
Pages
102-108
Citations
1749
Access
Closed

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Cite This

Xiaowei Li, Manman Geng, Yizhao Peng et al. (2020). Molecular immune pathogenesis and diagnosis of COVID-19. Journal of Pharmaceutical Analysis , 10 (2) , 102-108. https://doi.org/10.1016/j.jpha.2020.03.001

Identifiers

DOI
10.1016/j.jpha.2020.03.001
PMID
32282863
PMCID
PMC7104082

Data Quality

Data completeness: 86%