Abstract

Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS cases were the patients who had been exposed in nosocomial transmission at 16 hospitals. The epidemic lasted for 2 months and the government quarantined 16,993 individuals for 14 days to control the outbreak. This outbreak provides a unique opportunity to fill the gap in our knowledge of MERS-CoV infection. Therefore, in this paper, we review the literature on epidemiology, virology, clinical features, and prevention of MERS-CoV, which were acquired from the 2015 Korea outbreak of MERSCoV.

Keywords

OutbreakMedicineMiddle East respiratory syndromeTransmission (telecommunications)Middle East respiratory syndrome coronavirusEpidemiologyPneumoniaAtypical pneumoniaCoronavirus disease 2019 (COVID-19)PediatricsInfection controlSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyEnvironmental healthIntensive care medicineDiseaseInternal medicineInfectious disease (medical specialty)

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Year
2018
Type
review
Volume
33
Issue
2
Pages
233-246
Citations
222
Access
Closed

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Myoung‐don Oh, Wan Beom Park, Sang‐Won Park et al. (2018). Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea. The Korean Journal of Internal Medicine , 33 (2) , 233-246. https://doi.org/10.3904/kjim.2018.031

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DOI
10.3904/kjim.2018.031