Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Abstract

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the prior position statements, published in 2012 and 2015, on the management of type 2 diabetes in adults. A systematic evaluation of the literature since 2014 informed new recommendations. These include additional focus on lifestyle management and diabetes self-management education and support. For those with obesity, efforts targeting weight loss, including lifestyle, medication, and surgical interventions, are recommended. With regards to medication management, for patients with clinical cardiovascular disease, a sodium–glucose cotransporter 2 (SGLT2) inhibitor or a glucagon-like peptide 1 (GLP-1) receptor agonist with proven cardiovascular benefit is recommended. For patients with chronic kidney disease or clinical heart failure and atherosclerotic cardiovascular disease, an SGLT2 inhibitor with proven benefit is recommended. GLP-1 receptor agonists are generally recommended as the first injectable medication.

Keywords

Affiliated Institutions

• KU Leuven BE
• Massachusetts General Hospital US
• Harvard University US
• University of Leicester GB
• Leicester General Hospital GB
• Universitair Ziekenhuis Leuven BE
• Università Cattolica del Sacro Cuore IT
• Yale University US
• King's College London GB
• National Institute of Diabetes and Digestive and Kidney Diseases US
• Steno Diabetes Centers DK
• Duke University US
• University of North Carolina at Chapel Hill US
• University of Copenhagen DK
• Aristotle University of Thessaloniki GR
• National Institutes of Health US

Related Publications